Trade Name(s):

Arthron

Available

100 mg

Dose

100 mg three times weekly (Monday, Wednesday, Friday)

Indications

Treating longstanding inflammation associated with rheumatoid arthritis, lupus, and a number of other autoimmune disorders

Side Effects

The most serious side effect is damage to the retina in the back of the eye, occurring in 1 in 1,000 treated patients. This is generally reversible if caught early but could lead to loss of vision, especially color vision, if not properly monitored. The optometrist or ophthalmologist can pick up these changes in the eye before the patient experiences any symptoms. Stomach upset and changes in the skin pigment (most common with quinacrine) are less serious side effects. Patients with certain enzyme deficiencies may experience anemia after starting quinacrine.

Monitoring

An eye exam is recommended upon initiation of therapy, then every 6-12 months thereafter while taking this medication. Blood counts are recommended every 3-6 months on amodiaquine or quinacrine. Testing the level of an enzyme known as G6PD is prudent before starting quinacrine.

Important Points to Know

Notify the eye doctor concerning any changes in vision. Taking the medication with food may decrease stomach upset. Protective clothing should be worn to minimize sensitivity to the sunlight. These drugs may take 3-6 months to demonstrate significant effects on joint inflammation but may reduce skin manifestations of lupus within 1 or 2 months.

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1921 N. Webb Rd. Wichita, KS 67206
Phone: (316) 612-4815
After Hours: (316) 262-6262
Mon - Thurs: 8:00am - 5:00pm
Friday: 8:00am - 12:00pm
Sat - Sun: Closed