Trade Name(s):
Available
Dose
Indications
Treating serious complications of vasculitis or myositis
Side Effects
Anemia, low white blood cell or platelet counts, nausea, vomiting, diarrhea, rash, and mouth sores are more common side effects. Patients taking this drug are more susceptible to infection. Less commonly, an increase in liver enzymes, impaired fertility (males and females), nerve damage, seizures, agitation, and lung impairment have been reported.
Monitoring
Baseline blood counts, kidney and liver function studies should be obtained. Blood counts can be repeated every 2-4 weeks initially and every 1-3 months thereafter while taking this medication.
Important Points to Know
While mild nausea may resolve or improve with continued use of this medication, report any persistent nausea or vomiting to your provider. Watch for signs and symptoms of infection, rashes, or other skin reactions. While lung damage is rare, report any new difficulty breathing to your health care provider.