Trade Name(s):

Arava

Available

10 mg, 20 mg, and 100 mg tablets

Dose

10 to 20 mg daily; 100 mg daily for 3 days may be used as a "loading dose"

Indications

Treatment of rheumatoid arthritis; may be useful for treating other rheumatic diseases as well

Side Effects

The most common side effects are diarrhea, nausea, rash, and reversible thinning of the hair. Elevation in liver enzymes can occur, and there may be a slight increased risk of respiratory infection

Monitoring

Blood count and liver enzymes monthly for the first 3 months, then every 2 months while taking this medication

Important Points to Know

Take this medication with food to reduce gastrointestinal side effects. It should not be used in patients with chronic liver disease. Influenza (injectable, not oral) and pneumococcal vaccinations should be considered if not up to date. This drug is not to be used during pregnancy! Women who desire to become to become pregnant should first clear this medication from their body by using a cholestyramine for 11 days.

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