Trade Name(s):
Available
Dose
Indications
Treatment of refractory cutaneous (skin only) lupus; has also been used to treat Beh disease and cutaneous vasculitis
Side Effects
A rash may develop and is more commonly seen in patients allergic to sulfa drugs. Nausea and vomiting are infrequently seen. Anemia may also develop and is more common in patients who are of Afro-American or Mediterranean descent. Low white blood cells, elevations of liver enzymes, and nerve pain may occur in certain individuals.
Monitoring
Baseline blood counts and G6PD level (this enzyme deficiency makes patients prone to anemia) as well as kidney and liver enzymes are recommended. Blood counts can be repeated monthly until stable and every 3-6 months thereafter. Blood chemistries may be repeated every 6 months or so.
Important Points to Know
Patients with a deficiency in G6PD should not take this drug. Patients allergic to sulfa drugs and certain diuretics are more prone to allergic reactions to dapsone. To minimize stomach side effects, this medication should be taken with food.