Trade Name(s):

Prednisone, e.g.

Available

oral solution 5 mg/mL, 5 mg/5 mL; syrup 5 mg/5 mL; tablets 1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg, 50 mg

Dose

N/A

Indications

To reduce inflammation in joints or other regions of the body, or at higher doses to suppress excess activity of the immune system

Side Effects

Increased appetite, weight gain, fluid retention, hypertension, elevated blood sugar (potentially leading to diabetes), hardening of the arteries, cataract formation, glaucoma, osteoporosis, delayed wound healing, increased susceptibility to infection, development of “moon face,” and acne. Note: The frequency and severity of these side effects is highly variable depends on the dose and duration of therapy.

Monitoring

N/A

Important Points to Know

It is very important to take this medication as directed. Do not discontinue the drug abruptly after long-term use, which can lead to withdrawal symptoms. Stopping smoking and using measures that reduce cholesterol may decrease cardiac risks. Each patient should ask the health care provider about how long he/she can expect to take this medication. Any individual taking or anticipated to be taking corticosteroids for greater than 3-6 months should receive bone density monitoring and measures to prevent osteoporosis. In diabetics, and in certain patients on higher doses or at risk for high blood sugars should be instructed on diet and the importance of monitoring blood sugars levels. The health care provider should be notified of any vision changes, increased thirst or urination, swollen feet or ankles, shortness of breath, or signs of infection.

Other corticosteroids include methylprednisolone (Medrol), and dexamethasone (Decadron).

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